Side effects of Clomiphene

Most people taking Clomid (Clomiphene) report mild side effects, which have disappeared after stopping treatment. It is important, however, that all patients report side effects to their physician. Most people with Clomid are not serious, but they can become serious and may require treatment. Serious side effects that require immediate treatment are possible.

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The most common side effects of Clomid (Clomiphene) are swelling and pain in the stomach or pelvic area and hot flashes or flushing of the skin. Less common, but disturbing, are vision problems. These may include blurred vision, random flashes of light, sensitivity to light, yellowing of the eyes and skin, decreased vision and double vision. They are also less common, but potentially serious are weight gain and lack of air.

Other less common side effects of Clomid include breast pain, dizziness, lightheadedness, headaches, irregular or heavy periods, bleeding between periods, nausea, vomiting, restlessness, tiredness, depression and insomnia.

Once the medication is stopped, the side effects will go away, too.

Possible side effects of Clomid (Clomiphene) include:

  • Enlarged and sensitive ovaries (14%)
  • Heat (11%)
  • Abdominal sensitivity due to enlarged and sensitive ovaries (7.4%)
  • Abdominal distension (5.5%)
  • Breast tenderness (2.1%)
  • Vaginal dryness or thicker cervical mucus (percentage of occurrence not available)
  • Nausea and vomiting (2.2%)
  • Anxiety and insomnia (1.9%)
  • Vision Disorders (1.6%)
  • Headache (1.3%)
  • Abnormal uterine bleeding (blemishes) (0.5%)
  • Mood changes and fatigue (0.3%)

There is a possibility that clomiphene causes birth defects if taken after becoming pregnant. Stop taking this medication and tell your doctor immediately if you think you have become pregnant while taking clomiphene.


Tracy C. Tracy C. avatar

Good evening, girls! I tried to get pregnant lots of times and it did not work, later I was diagnosed with folliculogenesis. The doctor suggested laparoscopy instead of hormonal therapy, but I decided for the treatment with Clomid, so I took it for three months (the first month was 1/4 of the tablet starting from the 5th day of the cycle, and the other two months were 1/2 of the pill each) and the result met all expectations – I became pregnant, with twins! Ripened two follicles and went out two egg cells. Given birth without problems. Try it! I think that any drug treatment is better than surgical intervention!

Anna Anna avatar

This drug is effective! I could not get pregnant for a 5 years, the doctor prescribed the Clomid. A month later, I became pregnant! Remember that this drug can not be taken more than 5-6 times (stimulation cycles) in life otherwise, it is possible to re-stimulate the early menopause. While taking it felt normal, but sometimes there was nausea and sweating.